![]() ![]() Cornelian cherry fruits are famous for being endowed with antibacterial, anticancer, antioxidant, antidiabetic, anti-inflammatory, and hypoglycemic functions 15. It is recently grown in Asia and the interior of the European continent 14. Besides, it causes a serious induction in reactive oxygen species (ROS) generation and apoptosis in human cells 4.Ĭornelian cherry ( Cornus mas L.) is a plant with olive-shaped, scarlet-coloured and sour-tasting fruits that has been cultivated in gardens for 4000 years. According to the studies on experimental animals, exposure to diniconazole is resulted in thyroid, liver dysfunctions, kidney failures, tachycardia and malformed fetus formation 12, 13. Although it is widely used in agricultural production processes, diniconazole was proven to be a suppressor for plant growth, chlorophyll synthesis and photosynthesis 8, 9, 10, 11. 4 stated that its long half-life duration and highly lipophilic character let diniconazole fungicide have crucial risk potential for untargeted organisms. It is classified as a systemic fungicide that functions in the inhibition of the ergosterol synthesis, particularly in 14α-demethylation step of the biosynthesis via lanosterol-14 α-ademethylase enzyme 6. Plant diseases such as brown rust, powdery mildew, Septoria and scab formation are only a few of the problems in which the diniconazole fungicide is employed 7. Scientific efforts have focused on unwanted health risks on untargeted organisms caused by repeated and global employment of fungicides 5.ĭiniconazole is a triazole type with an excellent antifungal capacity in protection of fruits, vegetables, cereals and tea plants against several diseases through therapeutic and preventive practices 6. Despite their large scale uses and economic benefits in agricultural areas, overexposure to various pesticides carries high risks for the environment and biota.Īs a multi-member pesticide family, triazoles have become one of the most commonly applied fungicides due to their effectiveness, systemic motion, wide spectrum, and versatile usage for suppressing plant diseases and yield loss due to pathogenic fungi 3, 4. Pesticides are biocidal substances which have been indispensably utilized in crop production for an effective fight against pests such as insects, fungi, herbs and mites 2. Since plant diseases, weeds and pests are the most considerable concerns for adequate crop production worldwide, the pest control is a crucial step for eliminating the yield losses 1. mas extracts induced a dose-dependent prevention and amelioration in all damages arisen from diniconazole application.Īgriculture is a vital spot for economic development for many countries. The meristematic cell damages induced by diniconazole were indistinct transmission tissue, epidermis cell deformation, thickening of the cortex cell wall and flattened cell nucleus. Diniconazole caused significant rises in malondialdehyde content and the total activities of superoxide dismutase and catalase enzymes. Mitotic index decreased, while chromosomal aberrations increased following diniconazole application. Diniconazole application caused a significant reduction in germination percentage, root elongation and total weight gain. cepa bulbs were divided into six groups which were treated with tap water, 0.5 g/L CME, 1.0 g/L CME, 100 mg/L diniconazole, 0.5 g/L CME + 100 mg/L diniconazole and 1.0 g/L CME + 100 mg/L diniconazole, respectively. For this aim, physiological, cytogenetic and biochemical parameters as well as the meristematic cell damages were investigated in A. mas fruit extract (CME) against the toxic effects of diniconazole on a model organism, Allium cepa L. The present study was designed to evaluate the preventive efficiency of C. Diniconazole, a broad-spectrum fungicide, is employed extensively. Cornelian cherry ( Cornus mas L.) is a medicinal plant with antioxidant-rich fruits. ![]()
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